Dermaden Advanced Wound Care Cream box and tube under a glass dome on a mossy rock, with an alpine lake and mountains at sunrise

Derma Den USA - Clinically* Formulated Skincare, Delivered Online

Derma Den USA delivers clinically* formulated skincare with full ingredient transparency, starting with Dermaden® Advanced Wound Care Cream.

One Cream. Made in Israel. Delivered Straight to Your Door.

1Product, on purpose: Dermaden® Advanced Wound Care Cream
5Active mechanisms in one thin protective layer
50States we ship to, direct to your door
DirectFrom us straight to your front door: no stores, no middleman, no retail markup

Derma Den USA brings one product to the United States: Dermaden® Advanced Wound Care Cream, developed and made in Israel. There are no stores and no resellers in between: you order here, and we ship your Dermaden straight from us to your front door, anywhere in the 50 states.

Dermaden is made for serious wounds that need care every day: ulcers that are slow to close, including diabetic and venous leg ulcers, pressure sores on someone who spends long hours in a bed or chair, burns once they have been cooled, and the skin around a cold sore. A thin layer forms a flexible protective membrane over the area, a little like a temporary dressing, that helps keep it moist and comfortable while the skin does its own work of recovering.

One cream, explained properly, with a real team on the phone.

How Dermaden Works

One thin layer between cleaning and covering, doing five jobs at once.

Dermaden® Advanced Wound Care Cream uses the maker's NMBM technology: a Natural Matrix Bio-Polymer Membrane. Spread a thin layer after cleaning, and it settles into a flexible protective membrane that works like a light, temporary dressing.

It fits the moist-and-covered approach: it helps keep the area moist and balanced, then your usual breathable dressing goes on top. Dermaden is naturally derived, contains no antibiotics, and is made in Israel.

Read the full science behind the NMBM layer →

  • Protective barrier

    Covers and shields the area, like a temporary dressing.

  • Moisture balance

    Helps keep the skin from drying out, without leaving it soaked.

  • pH balance

    Helps keep the skin's surface at a balanced pH.

  • Fluid management

    Helps manage excess fluid from the wound area.

  • Nourishing amino acids

    Supplies amino acids that nourish the skin.

What Goes Into Every Tube

Dermaden is built around one job: protecting skin while it recovers. Here is what that means in practice.

  • Naturally derived: built on the maker's Natural Matrix Bio-Polymer Membrane technology rather than harsh chemical actives
  • No antibiotics: Dermaden works through a physical protective layer, so it can be part of an everyday routine
  • 5 active mechanisms: protective barrier, moisture balance, pH balance, fluid management and nourishing amino acids
  • An NMBM protective layer: a thin, flexible membrane that settles over the skin and works like a light, temporary dressing
  • Made in Israel: developed and manufactured in Israel, imported and sold in the US by Derma Den USA
  • A thin layer, 1 to 3 times a day: a little goes a long way; follow the directions printed on the pack
  • Under a breathable dressing: the cream protects the surface, a breathable cover keeps it clean and stops rubbing
  • Two sizes: 1.35 fl oz (40 ml) for a first try or a travel kit, 3.38 fl oz (100 ml) for ongoing care at about 27% less per ml

Clean the skin. Add a thin layer of Dermaden. Cover it with a breathable dressing. That is the whole routine.

Dermaden Advanced Wound Care Cream tube and box

Discover Dermaden.

Dermaden® Advanced Wound Care Cream

$49.001.35 fl oz (40 ml)

A naturally derived cream that forms a protective barrier over ulcers, sores and burns, and helps keep the area moist and comfortable while the skin recovers. Contains 5 active mechanisms and no antibiotics. Made in Israel.

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One Product, Made in Israel, Shipped Straight to Your Door

Derma Den USA exists to get one well-made wound care cream into the hands of the people who look after wounds every day, at home.

Most wound care happens far from a clinic. It happens in kitchens after a hot pan slips, at a bedside where someone is caring for a parent, beside someone living with an ulcer that is slow to close. The people doing that care need something simple they can trust and use every day.

Dermaden was developed and is made in Israel. We bring it to the United States and sell it directly to customers online, and ship it straight to your door, so there is no store markup and no reseller between you and us. Keeping to one product means we can explain it properly, answer questions about it in detail, and make sure every tube we send out is the real thing.

We describe what Dermaden does in plain words: it protects, it helps keep the skin moist and comfortable, and it supports the skin's own natural recovery. Our guides cover the everyday care around it, from cooling a burn to turning someone in bed.

Questions? Reach us at in**@********us.com or call +1 (848) 389-6474.

We Ship Nationwide

All 50 states, direct to your door.

Order online and Dermaden® ships from us to anywhere in the United States: 1.35 fl oz (40 ml) for $49, good for a first try or a travel kit, or 3.38 fl oz (100 ml) for $89, about 27% less per ml for ongoing care. Shop Dermaden.

Tested at Sheba Medical Center, Used on More Than One Kind of Wound

Wound care is what Dermaden® is made for. Here is where it has been tested, and the wounds it is registered for.

Dermaden®'s NMBM formula was tested against standard dressings in a randomised pilot trial at Sheba Medical Center, Israel's largest hospital, on hard-to-close venous leg ulcers. The trial was published in the Journal of Wound Care in 2020. Read the published trial.

In Israel, Dermaden® is registered with the Ministry of Health as a wound dressing whose listed uses include diabetic foot wounds, pressure sores and bedsores, burns and necrotic wounds. Our guides also cover the skin around cold sores and fever blisters.

In the United States, Dermaden® is sold as a cosmetic. Use it as directed on the pack.

Questions About Dermaden? Talk to Our Team.

Tell us what you're caring for, and we'll help you choose a size and use Dermaden the right way.

Our own team answers every call and message, whether you are caring for yourself, a child or a parent at home.

Shop at dermadenus.com, call +1 (848) 389-6474, or email in**@********us.com. Prefer to write? Use the form and we'll get back to you.

Send us a message and our team will get back to you.

Frequently Asked Questions

What is Dermaden?

Dermaden® Advanced Wound Care Cream is a naturally derived cream developed and made in Israel. When you spread a thin layer over the skin, it settles into a flexible protective membrane that works like a light, temporary dressing. That layer helps keep the area moist and comfortable while the skin does its own work of recovering. Derma Den USA imports it and sells it directly to customers across the United States.

How does Dermaden work?

Dermaden uses the maker's NMBM technology, short for Natural Matrix Bio-Polymer Membrane. The box lists 5 active mechanisms: a protective barrier that covers and shields the area, moisture balance so the skin neither dries out nor gets soaked, pH balance at the skin's surface, management of excess fluid, and amino acids that nourish the skin. It does all five in one thin layer, which is why a little goes a long way.

Has Dermaden been clinically studied?

Yes. The technology in Dermaden (NMBM) was tested in a pilot randomised clinical trial at the Department of Dermatology, Sheba Medical Center in Israel, registered as NCT01770509 and published in the Journal of Wound Care in 2020. It was used alongside compression stockings for four weeks and compared with conventional dressings; the researchers found it as safe and as effective as conventional care in that small study. <a href="https://dermadenus.com/wp-content/uploads/2026/10/sheba-clinical-trial-dermaden-nmbm-journal-of-wound-care-2020.pdf" target="_blank" rel="noopener">Read the full study (PDF)</a> or see the summary on <a href="https://dermadenus.com/our-science/">Our Science</a>.

What do people use Dermaden for?

People use it in daily wound care: on minor kitchen and household burns once they have been cooled under running water, on the skin of someone who spends long hours in a bed or chair, on diabetic ulcers and other wounds that are slow to close, and on the skin around a cold sore during a flare-up. Each of our wound care guides explains the full routine for that situation and where Dermaden fits in.

How do I apply it?

Wash your hands, rinse the area gently with clean water or saline and pat the skin around it dry with a clean cloth or gauze. Spread a thin, even layer of Dermaden over the area. You do not need a thick coat: the layer forms on its own as it settles. Then cover with a breathable dressing that suits the size and type of the wound.

How often should I use it?

A thin layer one to three times a day, as directed on the pack. Many people apply it when they change the dressing: in the morning, in the evening, and again if the dressing gets wet or dirty during the day.

Do I need a dressing on top?

Yes, for most wounds. Dermaden protects and balances the surface; a breathable dressing on top keeps the area clean, stops clothes and sheets from rubbing it, and holds the moist environment in place. Use a non-stick pad for burns and fragile skin, a film or foam dressing for areas that rub, and change it whenever it gets wet or dirty.

Which size should I buy?

The 1.35 fl oz (40 ml) tube is $49. It suits a small area, a first try, a travel kit or a kitchen drawer. The 3.38 fl oz (100 ml) tube is $89 and costs about 27% less per ml, so it is the better choice for ongoing care, such as a caregiver's daily routine or a larger area.

What is in Dermaden? Does it contain antibiotics?

Dermaden contains no antibiotics and no active drug ingredient: it works through a physical protective layer. Its ingredients include purified water, beeswax and carnauba wax, glycerin and sorbitol, plant-derived fatty acids, fructose, the amino acids L-lysine, glycine, histidine and arginine, and phenoxyethanol as a standard preservative. The full list is on our <a href="https://dermadenus.com/our-science/">Our Science</a> page and printed on the box. In a patch test on 50 volunteers, no skin irritation was reported.

Where do you ship, and how does ordering work?

We ship to all 50 states. Choose your size and quantity, check out securely on our site, and your order ships from us straight to your front door. We sell only through this website, so there are no stores or resellers in between.

How can I contact Derma Den USA?

Call +1 (848) 389-6474, email in**@********us.com, or use the contact form on this page. Our own team answers, whether you have a question before ordering, need help choosing a size, or want to ask about an order you have placed.

Dermaden® Advanced Wound Care Cream, Made in Israeldermadenus.com+1 (848) 389-6474